Heartburn and acid reflux are miserable, routine complaints most people struggle with, particularly after a heavy meal or spicy snack. That chest or throat burn? Your body’s trying to communicate that something’s wrong. The good news is, there are many great treatments available, whether you need instantaneous relief or ongoing control. Here’s a handy, no-nonsense primer on six of the best available treatments.

1. Antacids: Fast Relief When You Need It Most
Antacids are usually the first line of defense. Over the counter, they neutralize stomach acid, providing fast but short-term relief. Favorites are Tums, Gaviscon, Mylanta, and Alka-Seltzer. Liquid antacids generally work faster than tablets.
While good for intermittent heartburn, antacids are not suitable for ongoing symptoms. Side effects can include diarrhea or constipation, depending on the composition. They’re usually safe when pregnant, especially those that have aluminum salts in them, but it’s always a good idea to consult with a healthcare professional.
2. H2 Blockers: For More Extended Symptom Relief
If your heartburn lingers a bit longer or occurs more frequently, H2blockers might be a better option. These although idine (Pepcid), cimetidine (Tagamet), and nizatidine (Axid), lower the level of acid your stomach makes by inhibiting histamine.
They typically begin working within 30 to 90 minutes and stay active for several hours. Although they are over the counter, they are also prescribed for more long-standing cases under a doctor’s guidance. Note: Ranitidine (Zantac) was removed from sale in 2020 due to safety concerns, so it is no longer recommended.
Side effects are unusual but could include headaches, dizziness, or an upset stomach.
3. Proton Pump Inhibitors (PPIs): First Line of Treatment for Chronic Reflux
When symptoms are more intense or occur more often, PPIs are generally the better choice. Medications like omeprazole (Prilosec), lansoprazole (Prevacid), and esomeprazole (Nexium) work by reducing acid output at the source—the lining of the stomach.
Although PPIs are not short-term relief, they are potent enough to fix esophageal injury caused by acid reflux. They are usually prescribed for a short term (about 14 days), but some will need ongoing treatment.
Side effects are uncommon but may include headaches, changes in bowel movements, and, with prolonged use, an insignificantly increased risk of infections or bone fractures. Always consult with your doctor if pregnant, lactating, or on other medications.
4. Prokinetic Agents: When Motility Has to Be Boosted
For those who are not easily responsive to usual treatments, prokinetic drugs may be prescribed. These drugs—such as metoclopramide (Reglan)—help the digestive tract work more efficiently and improve the functioning of the lower esophageal sphincter such that reflux is less likely.
These medications are typically only taken as required because of possible side effects like tiredness, drowsiness, diarrhea, or, in some instances, movement disorders. They’re under close observation by medical staff if administered.
5. Combination Medications: Dual-Action Relief
Others like better relief with combination medications that blend quick-acting and longer-acting components. Zegerid, for example, blends a PPI (omeprazole) with sodium bicarbonate (an antacid), and Pepcid Complete has both an H2 blocker and antacids.
These combinations can be especially helpful for people with breakthrough symptoms even after treatment.
6. Home Remedies: Natural Options to Explore
For individuals who prefer more natural approaches, a couple of home remedies can offer subtle relief for mild symptoms:
- Ginger (in tea or supplement form) contains anti-inflammatory chemicals that might calm the digestive system.
- Chamomile tea can also temper irritation and facilitate relaxation.
- Apple cider vinegar, taken diluted in water, is a common folk remedy—though there’s limited evidence, and it can make symptoms worse for some individuals.
- Baking soda and water will also neutralize stomach acid, but it should be taken carefully, particularly in individuals with kidney or heart diseases.
Remember, although these remedies are useful, they’re not a replacement for medical attention in severe or chronic cases.
When to See a doctor
If you’re needing to take heartburn medication more than twice a week, or if you have symptoms such as difficulty swallowing, ongoing pain, or unintended weight loss, it’s time to visit a healthcare provider. If left untreated, acid reflux can advance to more severe situations like esophagitis, ulcers, or even precancerous changes in the esophagus.
The appropriate treatment—usually a combination of medication, lifestyle changes, and professional counseling—can provide long-term relief and enable you to eat again, without the pain.